WebThe reason is that the IC50 curve is not linear. It is a saturating function. In its simplest form, it is a square hyperbola and can be written as follows: % inhibition = 100 [I]/ {IC50 +... WebThe 50% inhibitory concentrations (IC50) were measured by viability assays treated with different concentrations of cisplatin. Flow cytometry and Western blotting were used for quantification of drug-induced apoptosis. Results: The ovarian cancer MCS showed a proliferation-stagnant but invasive phenotype when resuspended.

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Web11 Apr 2024 · Interestingly, IC50 values of MEISi were negatively correlated with MEIS1/2/3 protein expression in PCa cell lines (Figure 1, Figure 2 I). IC50 values of PC-3, DU145, 22Rv-1 and LNCaP were 21.95 µM, 17.96 µM, 3.18 µM and 2.87 µM , respectively. We also tested MEISi in normal prostate cell line PNT1A and human dermal fibroblasts (Figure S3 A ... WebIC 50 is a quantitative measure that indicates how much of a particular inhibitory substance (e.g. drug) is needed to inhibit, in vitro, a given biological process or biological … tithe in secret

IC50 - Wikipedia

WebThe half-maximal inhibitory concentration (IC50) was calculated using GraphPad Prism software (GraphPad Software, version 6.0 for Windows, San Diego, CA, USA, 2012). 2.6 Monitoring of Hydrogen Peroxide Production in Collagen Hydrogels Web12 Jul 2024 · The project is about understanding and exploring factors affecting CYP450 isoform specificity and selectivity in drug metabolism and toxicity. ... and toxic drugs. DTI classifies 392 drugs reported in US-FDA’s Liver Toxicity Knowledge Base (LTKB) with AUC for ROC curves of 0.91-0.64 for different WHO ATC categories. ... and the IC50 values ... WebChinese Name: 孫嘉良 Other Name: SunCL - H-index: 34 (google scholar) Expertise : Nanostructured Materials, Graphene, Graphene Nanoribbon, Carbon Nanotubes, Nanoparticles, Electrochemical Sensor Research of Interest : - Synthesis and integration of sp2-nanocarbon materials (carbon nanotube, graphene, graphene nanoribbons … etc.) for … tithe in hebrew